Hawthorn Extract and its Health Benefits

Hawthorn extract, derived from the Crataegus species, is recognized for its broad spectrum of health benefits, particularly in cardiovascular and liver health, antioxidative properties, and potential as an anti-aging agent. Recent studies have illuminated these diverse benefits.

Vascular Protective Effects: Hawthorn extract has been found to offer vascular protective effects in cardiovascular diseases, aiding in the management of heart health (Zhang et al., 2023).

Antioxidative and Anti-aging Properties: A study demonstrated that hawthorn fruit extract could ameliorate oxidative damage in neuronal cells and prolong lifespan via the IIS signaling pathway, indicating its antioxidative and anti-aging properties (Wang et al., 2022).

Liver Health: Hawthorn extract plays potential roles in combating various liver diseases, showing promise in liver health management (Kim, Jang, & Lee, 2022).

Biomedical Applications: Research highlights the diverse biomedical applications of hawthorn, showcasing its versatility in health promotion (Ramadan & Khalil, 2022).

Lipid Metabolism and Gut Health: Studies have shown that dietary hawthorn extracts can positively affect lipid metabolism, skin coloration, and gut health (Tan et al., 2020).

Antithrombotic Benefits: Hawthorn leaf extract has been identified for its antiplatelet aggregation and antithrombotic benefits, contributing to cardiovascular health (Gao et al., 2019).

Serum Antioxidant Activity: Hawthorn extract has been observed to affect serum antioxidant activity, impacting cardiac indicators and growth performance, particularly in stress conditions (Ahmadipour, Kalantar, & Kalantar, 2019).

These findings elucidate the multifaceted benefits of hawthorn extract, underlining its potential in various health applications.


Zhang, L., Pan, J., Shi, H., Zhang, M., & Li, C. J. (2023). Advances in the study of the vascular protective effects and molecular mechanisms of hawthorn (Crataegus anamesa Sarg.) extracts in cardiovascular diseases. Food & Function.

Wang, X., Li, X., Li, L., Yang, X., Wang, J., Liu, X., Chen, J., Liu, S., Zhang, N., Li, J., & Wang, H. (2022). Hawthorn fruit extract ameliorates H2O2-induced oxidative damage in neuronal PC12 cells and prolongs the lifespan of Caenorhabditis elegans via the IIS signaling pathway. Food & Function.

Kim, E. J., Jang, E., & Lee, J. H. (2022). Potential Roles and Key Mechanisms of Hawthorn Extract against Various Liver Diseases. Nutrients.

Ramadan, J., & Khalil, M. (2022). Hawthorn, a promising plant with diverse biomedical applications. Bacterial Empire.

Tan, X., Sun, Z., Zhou, M., Zou, C., Kou, H., Vijayaraman, S. B., Huang, Y., Lin, H., & Lin, L. (2020). Effects of dietary hawthorn extracts supplementation on lipid metabolism, skin coloration and gut health of golden pompano (Trachinotus ovatus). Aquaculture.

Gao, P. Y., Li, S. S., Liu, K., Sun, C., Song, S. J., & Li, L. Z. (2019). Antiplatelet aggregation and antithrombotic benefits of terpenes and flavones from hawthorn leaf extract isolated using the activity-guided method. Food & Function.

Ahmadipour, B., Kalantar, M., & Kalantar, M. H. (2019). Cardiac Indicators, Serum Antioxidant Activity, and Growth Performance as Affected by Hawthorn Extract (Crateagus oxyacantha) in Pulmonary Hypertensive Chickens. Brazilian Journal of Poultry Science.

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